Biohaven is studying an investigational drug to help treat the symptoms of OCD. 

Biohaven is studying an investigational drug to help treat the symptoms of OCD. The investigational drug is called troriluzole and is a glutamate modulator. Glutamate is a key neurotransmitter in the brain and research indicates that there is excessive glutamate in areas of the brain involved in the obsessions and compulsions that OCD patients experience. Troriluzole is expected to normalize glutamate levels in these brain areas, and thus improve OCD symptoms.

To be eligible to take part in this study, you must:

1. Be between the ages of 18 and 65;
2. Have been diagnosed with OCD or have had symptoms of OCD for at least a year;
3. Be taking an OCD medication that you do not feel is fully helping your condition.

Please note: you do not need to have a formal OCD diagnosis. Also, there is no cost to you to participate and insurance is not required.

For more information and to enroll in the trial, go to OCDTrials.com

Fathers’ Experiences of Intrusive Thoughts in the Perinatal Period

Participants Needed! (Bournemouth University)

For my final year dissertation project, I am looking into Father’s Experiences of Intrusive Thoughts in the Perinatal Period.

It would be great to get responses regarding fathers’ experiences so we can better inform services and support fathers.

What is Involved?

Questionnaire on fathers’ experiences of intrusive thoughts in the perinatal period.

For how long?

Approximately 30 minutes.

Eligibility

18+ Father who has experienced intrusive thoughts in the perinatal period.

How do I participate?

Follow this link: https://lnkd.in/eGyQQdKf 

BU Ethics ID: 46804

Inviting all LGBTQIA+ people with OCD to participate in the first ever survey for LGBTQIA+ people with OCD.

Background:

Did you know that LGBTQIA+ people are 6-9x more likely to be diagnosed with obsessive-compulsive disorder (OCD) than their cisgender, heterosexual peers? LGBTQIA+ people experience unique identity-based stressors that may impact the development, severity, and maintenance of OCD. However, to date, current theories of OCD neglect to consider the unique experiences of LGBTQIA+ people with OCD.

Purpose:

• Understand how unique LGBTQIA+ experiences may impact the development, severity, and maintenance of OCD.
• Develop more inclusive theories about OCD for LGBTQIA+ people.
• Inform the development of more inclusive treatment practices for LGBTQIA+ people with OCD.

Get involved:

If you are LGBTQIA+ and have OCD, make your voice heard. To participate in the first ever survey for LGBTQIA+ people with OCD, email prideocd@bcm.edu or go to the survey directly at: tinyurl.com/uhsd963h

UK Charity, Orchard need participants for their new OCD survey on new or alternative forms of OCD therapy. 

This survey will help recruitment for OCD studies and those participating will be vital to the development of OCD treatments, which could help many others in the future.

Those participating must be 18 and over and self-identify as having OCD. They do not need to have an official diagnosis of OCD in order to participate. It will take no longer than 30 minutes to complete.

Below is the link to our survey: 

https://redcap.herts.ac.uk/surveys/?s=LETKTCCJPM

Researchers at the Yale School of Medicine are currently recruiting more families for the TABS  Study. The purpose of this study is to understand the relationship between genes and BFRBs.  The researchers are recruiting individuals affected by either trichotillomania or skin picking  disorder as well as both of their parents. Eventually, we hope that this research will teach us  more about the causes of BFRBs so that this knowledge can inform better treatments in the  future. Participating in this research involves providing a saliva sample for genetic analysis and  completing an online survey. Samples will be provided by mail – no site visit required! Please  email tabsstudy@yale.edu or call 203-745-0267 to learn more.

Study Information: 

Study Title: Genetic and molecular studies of developmental neuropsychiatric disorders  associated with cognitive and behavioral impairment

Study Sponsor: National Institute of Mental Health (K08MH128665, PI: Emily Olfson, MD PhD)  HIC: 0301024156

About the study: 

Your family has been invited to be part of a study of families in which a child has an Obsessive Compulsive Disorder (OCD) and his/her parents do not. The purpose of this study is to identify the  genetic factors that cause OCD using a family-based approach. This will greatly contribute to our  understanding of OCD and may help develop new therapies in the future. This study requires  participation from a child and both biological parents, can be done in-person or remotely and  participation will be compensated with a $100 Amazon gift card for the family. We are not able to offer  you a report of your genetic results because our studies are performed as research. Our research lab  does not offer any treatment.

What do we need from you to participate? 

1. Genetic Samples: we will obtain a blood sample and saliva sample for genetic analysis from the  child and both parents. If a family member is unable to come to Yale University in person for a  blood draw, we can send someone to your house to have this done at a convenient time for you.

2. Questionnaire: we will ask you to complete standardized questionnaires asking about how you  and your child think, feel, and behave as well as questions about your medical and psychiatric  history. These questionnaires can be completed from home, and we can assist with any  questions or concerns.

3. Interview: Once you have completed the questionnaires and returned them to us, we will  review them and set up a brief 15-20-minute phone call to review your responses.

If you have further questions or are interested in participating in our study, please contact us at  findgenes@yale.edu, call us at (203)-677-0842, or use the following link to complete our study interest  survey: https://yalesurvey.ca1.qualtrics.com/jfe/form/SV_a2z1a5YDogG154i.  

Thank you for your interest in participating in this research study! 

Study Information: 

Study Title: Genetic and molecular studies of developmental neuropsychiatric disorders associated with  cognitive and behavioral impairment

Study Sponsors: National Institute of Mental Health/NIH/DHHS, Simons Foundation, The Regents of the  University of California, San Francisco (UCSF), and The Yale Child Study Center

HIC: 0301024156

We are looking for adults 18 years and above who suffer from self-reported phobias, including emetophobia, to take part in a study examining the impact on working memory. Emetophobia is defined as the disproportionate fear of vomiting or other people vomiting and is associated with the hypervigilance of potential trigger situations. Participants do not need to self-report a phobia in order to take part.

The application has been reviewed by the School of Psychology and Clinical Language Sciences Research Ethics Committee and has been given a favourable ethical opinion for conduct [2023-007-BP].

The entire experiment is expected to take no more than half an hour.

Participants will be asked to complete:

• A questionnaire recording basic demographic information
• A word-pairing task, with a descriptive task part-way through
• A final questionnaire regarding your experience with vomit

Location:

• The experiment will take place online

Are you eligible?

• 18 years or older
• With or without a self-reported phobia
• Have access to a computer – this study is conducted online

The experiment is entirely voluntary, and participants can leave at any given time without any adverse consequences.

SONA participants will receive 0.5 credits for their participation.

Link to the study: https://research.sc/participant/login/dynamic/66F522F1-6526-4B49-ADBC-A6BE89F39DF2

If you have any questions about the study, please email:

Molly Harbor 

m.harbor@student.reading.ac.uk

The Center for Practice Innovations and the Center for OCD and
Related Disorders at Columbia University Department of Psychiatry
and the New York State Psychiatric Institute is seeking individuals
aged 18 years and older with symptoms of obsessive-compulsive
disorder (OCD) to participate in a research study. The study involves
participating in a survey that asks questions about preferences for
informational materials and resources about OCD, treatment
preferences and how OCD research should be prioritized.
Participation takes about 20 minutes. Your responses will be kept
confidential. All participants will have the opportunity to enter a
raffle to win a $100 Amazon gift card. You can take the survey by
clicking this link

Are you very CONCERNED with your appearance?
Do you often WORRY about your looks?
Do you CHECK your appearance many times a day?

If you answered yes to any of these questions, and if you are 18+ years old and live in the U.S., you may be eligible to participate in our smartphone research on severe body image concerns. This research is being conducted remotely (no in-person visits) by researchers at Massachusetts General Hospital and Harvard Medical School.

You may be compensated up to $257 for your participation.

For further information about participating in this study, please contact us at:
Email : BDDphonestudy@partners.org
Phone: +1 (877) 4MGH-BDD
Website: https://is.gd/bddphonestudy

Do you have a teen, ages 13-18, with OCD? If so, you and your child may be eligible to participate in a study examining the effect of Transcranial Magnetic Stimulation (TMS) on brain functioning in youth with OCD. In TMS, a magnet is used to stimulate the brain from outside the head. TMS is non-invasive and is generally well-tolerated in children. The goal of this study is to test whether TMS can improve the connections between areas of the brain that are responsible for stopping unhelpful behaviors. If successful, we hope this may improve teens’ ability to resist OCD compulsions and eventually lead to a new treatment option for teens with OCD.

Participation will consist of:

• One remote visit for a screening interview (approximately 1.5 hours)
• Two in-person visits for TMS, electroencephalogram (EEG), and computer tasks (approximately 2 hours each)
• After each visit, your child will be asked to complete brief electronic surveys sent via text message
• Compensation will be provided for each study visit

Please visit our website at https://www.anxiouskids.org/tms-study or call us at 401-432-1469 for more information.

The last two years of the COVID-19 pandemic has been a particularly challenging time for health care workers, including mental health care providers. The Evidence Based Treatment Centers of Seattle (EBTCS) is conducting a research study on factors associated with well-being in licensed mental health professionals who provide therapy services, with a particular focus on experiences of telehealth and potential changes in practice during COVID-19.

Study participation involves completing an online survey via SurveyMonkey. Most individuals take between 10-15 minutes to complete the survey. All data is completely anonymous. Names or other unique identifiers are not collected.

The study survey includes the following types of items: demographic data, information about work settings and activities, questions about well-being, ways of coping, and experiences of delivering services via telehealth. Additionally, for licensed therapists who provide dialectical behavior therapy (DBT), the survey also includes questions assessing perceptions of telehealth with high-risk clients and behaviors.

Risks for participating in the study are minimal. There is no compensation for participation.

Interested licensed therapists can click below to be taken to the study consent form and survey, or can contact Ariel Ravid, PhD, at aravid@ebtseattle.com.

Survey: https://www.surveymonkey.com/r/EBTCSwellbeing

Survey Password: wellbeing

Thank you for considering participating in this study!

Ariel Ravid, PhD and Travis Osborne, PhD

Co-Directors of Research

Evidence Based Treatment Centers of Seattle (EBTCS)

Are you an individual who has been diagnosed with Obsessive Compulsive Disorder (OCD)?

Are you interested in providing feedback on an innovative and novel smart-ring device to see how it detects behaviors that often occur in the context of OCD?

If yes, would you like to participate in a brief study at the University of Utah that involves:

*Completing an online feedback interview session with a study staff member

about how feasible or useful such a device will be, from your perspective?

*Providing your thoughts on the most useful features we should consider for this

device as we design it?

The study entails a brief semi-structured interview over the phone to determine

eligibility followed by just 1 remotely-conducted feedback session on Zoom where

you chat with a study staff member and complete a few brief scales about the

device for a total time commitment of just about 1 hour, and you can be

compensated up to $40 for your time!

Interested individuals can reach out to set up a phone screening to determine eligibility

with a staff member at the Treatment Mechanisms, Community Empowerment, and

Technology Innovations (TCT) Lab at the University of Utah – email us at

empowerlabU@gmail.com and we will schedule a phone screening with you right away!

We are recruiting participants who: Are at least 18 years of age; Have received a diagnosis of OCD; Have had at least one inpatient hospitalization for mental health concerns lasting at least 24 hours.

Individuals meeting these criteria may be eligible to participate in a study looking at the experiences of people with OCD who have had at least one inpatient hospitalization for mental health reasons. Participation involves answering questions in an online survey about your thoughts, feelings, and experiences related to your inpatient hospital stay(s).

This study is being conducted by Dr. Eric Storch, Ph.D. at Baylor College of Medicine, Houston, TX. For more information, please contact the study coordinator, Saira Weinzimmer at 713-798-3080 or email saira.weinzimmer@bcm.edu.

Note: Health information shared online is not secure. Please do not comment on this post with any private or personal health information.

Link: https://bcmpsych.sjc1.qualtrics.com/jfe/form/SV_dbUYIwnmtCsXhD8?fbclid=IwAR0rR5lFtWFukM8RBXyLzr-L_rBja0sxYB0uayoHND3HNu-AAayR0IfjLSk

We need your help. 

We want to know more about why people find it difficult to discard things and tend to save or collect items.

We are looking for people who have difficulties with hoarding objects.

If you would like to participate in this study, please contact us!

Phone/Text: +61493 132 561

Email: CPRlab@acu.edu.au

Study Inclusion Criteria: People with clinically significant problems with hoarding objects in their home, are above 18 years old and can complete questionnaires in English. 

Study Exclusion Criteria: people with psychosis, significant cognitive impairment, a neurological disorder, traumatic brain injury, or active suicidal ideation from the study.  

This study has been approved by the Human Research and Ethics Committee at the Australian Catholic University (No. 2020-151H). 

Purpose: Researchers at Suffolk University and the New England Center for OCD and Anxiety want to learn more about how exposure therapy works for teens with OCD by learning about different experiences in therapy for teens with OCD and how thinking effects behavior. 

Who: We are seeking teens 13-17 years old who are currently, or who have previously, been in exposure therapy for OCD. If you’re not sure if you have tried exposure therapy, ask our study team! Permission from your parent is required to do this study. 

What you will do: Complete a game and answer survey questions about your OCD and treatment you have tried online, which will take you about 35 minutes. Your parent can also participate by answering survey questions online. 

Why: You may help researchers learn information about important ways that treatment could be changed so that it works for more teens with OCD. 

You will receive: A self-help book for teens with OCD and a $10 Visa gift card!

If you are interested or have questions call, text, or email our study team:

Katrina, Study Co-Investigator

kdaigle@suffolk.edu

617-394-8876

Does your child suffer from OCD?

We are actively recruiting for a study at Massachusetts General Hospital to investigate the effect of transcranial direct current stimulation (tDCS) on neurocognitive functioning in pediatric OCD. tDCS is a non-invasive, painless, and safe form of brain stimulation. 

We aim to discover new non-medication treatment approaches for children with OCD using targeted and safe delivery of a weak current to the scalp. Please note that this is an investigational study, not a treatment study. This means that while we are not expecting benefits to you directly, we plan to use what we learn to inform future treatments. 

The study consists of 4 total visits:

• One remote/virtual screening visit 
• Three in-person visits, approximately 2 hours long each. 
  • Each visit will include computer tasks, questionnaires, electroencephalogram (EEG) and tDCS. 
• Compensation of up to $120 

Please visit our study website or reach out to our team if you are interested in learning more!

Study website: https://rally.partners.org/study/tdcs

McKenzie Schuyler, Study Coordinator

P: 617-726-5527

E: mschuyler@partners.org

Mathijs Van Der Drift, Study Coordinator

E: mvanderdrift@mgh.harvard.edu

Daniel Geller, M.D., Principal Investigator

E: dan.geller@mgh.harvard.edu 

Baylor College of Medicine would like to present the Latin American Trans-Ancestry Initiative for OCD Genomics, or LATINO. This new study seeks to collect the world’s largest ancestrally diverse sample of OCD cases (N = 5,000 Latin American individuals). This study will feature international collaborations with OCD clinics in Argentina, Brazil, Canada, Chile, Colombia, Ecuador, El Salvador, Paraguay, Peru, and Mexico, as well as OCD clinics in the U.S., including Houston, Miami, New Jersey, San Diego, and San Juan, Puerto Rico. This monumental study will address the current Latino representation gap in OCD genetic research by conducting a novel, wide-scale OCD genomic study with robust phenotyping. We hope that increased representation of Latin individuals will advance our ability to detect, diagnose, and treat individuals of Latino ancestry using precision medicine, as well as contribute to the diversification of OCD genomics as a whole. To get involved, email Latinostudy@bcm.edu or check out: latinostudy.org

Format: The study is conducted remotely via Zoom. Thus, we are recruiting English-speaking participants from anywhere in the world.

Duration: We plan to conduct this study till September 2022.

Text: Do you love possessions? Participate in our study!

We are looking for adults (aged 17+) with hoarding and/or compulsive buying problems to participate in a study about acquiring and saving behaviours. If deemed eligible after a short screening interview, you will be asked to complete a 3.5-hour session completing interviews, tasks, and questionnaires online via Zoom. You will be paid AUD$20/hr in the 3.5-hour session and will be given the opportunity to earn up to AUD$10 bonus prize money.

To register your interest, go to https://redcap.link/possession.study

To date, very little research on OCD has been conducted in older adults, hindering our understanding of how it presents in older adults, factors that may maintain symptoms, and the best methods for effective treatment. In particular, the role of family members and friends in maintaining or overcoming symptoms is unclear. The purpose of this research is to collect information from older adults with OCD, and (where possible) from a close family or friend, in order to help us develop an age-tailored treatment for late-life OCD.

We are seeking adults aged 60 years and older who experience symptoms of OCD, as well as their supporters (i.e., a friend or family member). Please note it is not necessary to have a supporter in order to participate in this study. Participation would require around 2.5 hours of your time, and involves completing an online survey and an interview with one of our researchers via phone or videoconference. Individuals who participate will receive USD$30 to thank them for their time.

If you are interested in receiving more information or participating in the study, please contact us at ceinwyn.attrill@mq.edu.au or +61 (2) 9850 8596.

The purpose of this study is to better understand the relationships between traumatic life events and OCD symptoms. Participation in this study will involve answering a series of online questionnaires via an anonymous link. The study is being conducted by Dr. Caitlin Pinciotti at Baylor College of Medicine in Houston, Texas.

The survey is available online and takes approximately 45 minutes to complete.

Email OCDTraumaStudy@bcm.edu or click to participate: https://tinyurl.com/zzw5shb6.

Individuals with Obsessive-Compulsive Disorder 

The University of Miami would like to invite you to participate in a graduate student’s  dissertation study examining the relationship between trial-and-error learning and OCD. The  study is fully remote and would take place online and over the phone. The current project’s aim  is to help clarify the relationship between OCD and habit learning, which we hope will  eventually lead to more effective treatments.

What is involved?  

If you agree to participate in this study, you will be asked to complete a web-based computer  task that involves learning the relationship between images of fruit on the screen by trial-and error button-pressing. The game should take about 25-30 minutes to complete.

Some participants who complete the computer task will also be invited to complete a 20  minute phone call with a member of our clinical research team and 10 minute online survey.  The phone call would involve a structured interview about mental health related symptoms.  The online survey would include questions about your mood, thoughts, and behavior.

If you are invited to complete the phone call, you will be able to schedule the interview at  designated times up to a week in the future.

Who is eligible? 

To participate you must be 18 years of age or older, have a diagnosis of obsessive-compulsive  disorder, and be fluent in English.

Compensation: Eligible participants will be compensated up to $30 for their time and effort.  For more information, please email us at paso@psy.miami.edu or call (305) 284-5394 Thank you!

We are conducting an anonymous, online research study to understand contamination-related OCD compulsions. This study involves a series of questionnaires regarding your compulsions and other symptoms.

To be eligible, you must:

• Be at least 18 years old
• Be fluent in English
• Have contamination-related OCD

This survey will take approximately 20 minutes. You will be entered into a raffle to win $40. You are guaranteed to have at least a 1/10 chance to win.

We will keep all information you provide confidential and anonymous. This means that we will

not ask for any identifying information in the survey with the rest of the questions. In order to

be entered into the raffle, you will follow a link to a second, separate survey for you to enter

your name and contact information. That way, it will be impossible to associate your specific

responses with your identity.

The link to participate is:

This study is being conducted by Dr. Jedidiah Siev at Swarthmore College. For more

information, please contact: soarlab@swarthmore.edu.

Hi everyone!

We’re looking for participants to fill out a survey as part of a study on adolescent mental health and wellbeing. Unrecognized and untreated mental health struggles among teens is an all-too-common issue. With this study, we are hoping to extract larger themes surrounding adolescent mental health in an effort to eventually create tools to improve pediatric mental health screening, monitoring, and early intervention.

Specifically, we’re hoping to have parents of teens aged 14-18 to fill out the survey. The survey should only take 10-15 minutes to complete, is completely anonymous, and can be done from wherever you are located. This study has been approved by the Research Ethics Board at the McGill University Health Center.

If you’d like to participate, follow this link to fill out the consent form and the survey: https://forms.gle/6eChCePBKoBQZ5S6A

If you have any questions, please don’t hesitate to message me or to email TrakadisLab.fmhs@mcgill.ca. We’d greatly appreciate your help!

All the best,

The Trakadis Lab

Have you been diagnosed with Obsessive-Compulsive Disorder (OCD)? For many patients with Obsessive-Compulsive Disorder (OCD), medication and/or CBT and ERP are effective treatment options. For some, these treatments are ineffective, and they are severely disabled by their OCD. Psychiatric neurocircuitry-based procedures (e.g., TMS, neurosurgery) represent one treatment modality that may be available for individuals not amenable to standard treatments. We are seeking to gain a better understanding  of the knowledge of and attitudes toward neurocircuitry-based procedures in those with OCD. We would appreciate your time in filling out this survey to help us reach this goal, no matter your level of knowledge or expertise on the topic.

Survey Link: https://tinyurl.com/patientperspectives  

Do you have experience of living with obsessive-compulsive disorder?

Have you used any mobile apps in the last 12 months to help manage your distress?

I am a trainee clinical psychologist currently enrolled on the Doctorate in Clinical Psychology programme at Lancaster University.

For my thesis I would like to explore the views of people who have been diagnosed with or self-identify as having OCD and have used mental health apps in the last 12 months.

I hope to find out what makes mental health apps helpful or unhelpful, so that treatments for people with this diagnosis can be better in the future.

If you would like more information, please contact Faromarz Nasiri by email at:f.nasiri@lancaster.ac.uk

Deep brain stimulation (DBS) is an advanced medical treatment that uses electrical impulses to ease symptoms from a variety of neurologic and psychiatric disorders. We design a treatment plan specific to you and your obsessive-compulsive disorder (OCD) symptoms to achieve the best results while minimizing side effects.

How does it work?

We start by pinpointing (via brain scans) the exact spot in the brain that is causing the problem. Then, we implant two electrodes into that area of the brain, which connects to a neurostimulator. The neurostimulator is implanted just under your skin, near the collarbone-like a pacemaker. This enables us to send electrical currents to your brain to ease your symptoms. Once the device is placed, we program the location, amplitude, duration, and frequency of the electrical pulse for the best result.

Is it effective? 

On average, 60% of severely ill and treatment-resistant OCD patients see results with DBS. Most patients feel symptom relief soon after the procedure, and the relief is typically long-term. DBS also often enables patients to reduce medication (and its unpleasant side effects).

Is it safe? 

Yes. The FDA has approved DBS for treatment-resistant OCD under a Humanitarian Device Exemption (HDE). The HDE recommends that treatment be rendered at institutions that have experience with this intervention. Mount Sinai is one of the few experienced institutions where DBS for OCD is available, and we have been using this procedure for more than a decade. There is a minimal chance that placing the stimulator may cause bleeding (1%) or infection (3%) in the brain- both of which usually do not have permanent consequences. DBS itself has minimal side effects, and most patients with OCD consider DBS to be overall less burdensome than medication.

Who is eligible? 

You are eligible for DBS if you have had severe OCD for at least 5 years, and you did not respond to all of the treatment methods below:

• Cognitive behavioral therapy (CBT) with expo ure and response prevention by an expert therapist for at least 25 sessions
• Two treatments with an SSRI at maximum dosage, for 18 weeks
• Treatment with an SSRI at maximum dosage, combined with an antipsychotic
• Treatment with clomipramine at maximum dosage, for at least 12 weeks

How do I make an appointment? 

Call our office at 212-659-8810 or email our research coordinator Sonia Olson at sonia.olson@mssm.edu, and have the last few notes from your psychiatrist or primary care physician faxed to us at 212-523-8342. After we have reviewed your records, we will call to set up an appointment for further assessment. DBS for OCD at Mount Sinai is covered by Medicare, Medicaid, and most insurance companies on a case-by-case basis

ACE-OCD is a clinical trial being run by Drs. Evelyn Stewart, a child and adolescent psychiatrist and professor at UBC, and Clara Westwell-Roper, a UBC Psychiatry Research Track Resident, at the Provincial OCD Program at BC Children’s Hospital Research Institute. Together they are investigating whether celecoxib, a non-steroidal anti-inflammatory drug often used for pain relief such as Advil, can help children and youth with Obsessive-Compulsive Disorder (OCD).

OCD is a condition that is characterised by unwanted upsetting thoughts or feelings (obsessions) that cause distress and anxiety and force individuals to perform actions or rituals they do not want to do (compulsions) to reduce the stress and anxiety caused by obsessions. OCD can interfere with daily activities, such as socializing, self-care, and school functioning. The usual treatments include cognitive behavioural therapy and medications called serotonin reuptake inhibitors, but almost half of children continue to experience symptoms despite these treatments.

Both genetic and environmental factors contribute to the development of OCD, but not all of these factors are understood. Research studies have suggested that proteins and cells related to inflammation may be affected in children and adults with OCD. Celecoxib belongs to a medication class called non-steroidal anti-inflammatory drugs (NSAIDS). A common NSAID that many children have taken previously is ibuprofen (Advil/Motrin), but it requires multiple doses per day to effectively reduce inflammation, whereas celecoxib is taken twice daily. NSAIDs such as celecoxib may limit inflammation and improve the function of neurons in parts of the brain involved in OCD symptoms.

This study will assess the effect of celecoxib on OCD symptom severity. Symptoms in participants receiving celecoxib (added to their usual treatment) will be compared to those receiving placebo, an inactive substance that looks identical to the test drug but contains no therapeutic or experimental ingredients. We expect that a total of 80 participants with OCD will be enrolled in this study, which is a single-site trial based at BCCH.

Health Canada, the regulatory body that oversees the use of natural health products/drugs/devices in Canada, has not approved the sale or use of celecoxib for OCD in either children or adults. Health Canada has allowed celecoxib to be used in this study.

The goal of this study is to determine whether 12 weeks of treatment with celecoxib added on to usual treatment results in improvement in OCD symptoms compared to placebo. This study is a randomized placebo-controlled trial, which means that half of participants will receive celecoxib and half will receive placebo, an identical capsule that does not contain the active drug. Participants may be assigned to either treatment. They will also continue their regular treatment (medication and/or psychotherapy) under the care of their regular doctor(s).

This is a Phase II study, which is undertaken after preliminary safety testing on a drug or treatment. Celecoxib has already been tested in previous studies for safety in children. Phase II studies are usually conducted on a small number of individuals. In this case, it will allow researchers to begin to find out what effect celecoxib has on OCD and to further evaluate its safety.

Who can participate:

1. Age 7-18 years

2. Resident of British Columbia

3. Diagnosis of moderate to severe OCD

4. Able to take medication twice daily in capsule form (in whole form or sprinkled contents)

5. Negative pregnancy test (either serum or urine) in participants with child-bearing potential

6. Use of highly effective and/or double barrier contraception, or abstinence, in participants with child-bearing potential

You are not eligible to apply if you meet the non-eligibility criteria below*

Potential Risks

NSAIDs are well-tolerated in children at doses and durations exceeding those delivered in this trial, with the most common treatment-related adverse events including mild gastrointestinal symptoms that are mitigated by taking the medication with food. These include abdominal pain, nausea, diarrhea, and stomach upset.

Serious adverse events are very rare in children (<0.01%); these include gastrointestinal bleeding, ulcer, or perforation; kidney disease; and allergic reactions.

End date

September 30, 2023

Study Involvement

The initial survey will take about 30 to 40 minutes, and subsequent surveys can take between 15 to 20 mins.

Contact

Interested participants can contact us at aceocd@bcchr.ca and our research team will then arrange a phone call with you to provide more information about the study.

*Children and young adults are not eligible to participate in this study if any of the following apply:

• They have been previously diagnosed with or develop conditions that would increase their risk of harm with NSAID use, including kidney or liver disease, gastrointestinal bleeding or peptic ulcer disease, inflammatory bowel disease, bleeding disorders, severe asthma, or NSAID allergy.
• They have a current major depressive episode, psychosis, suicidality, or active substance use.
• They have an active infection or are taking antibiotics.
• They have used any NSAID at any dose more than 3 times per week in the 2 months prior to participation.
• They currently take steroids (IV, oral, or inhaled) or drugs that may interact with celecoxib (detailed list included in Appendix A).
• There is an abnormality identified on baseline blood work including liver enzymes, kidney function, and blood cell counts, or they have a form of an enzyme that metabolizes celecoxib that will significantly increase their levels.
• Changes have been made to CBT or other psychotherapy in the 4 weeks prior to participation
• They have started a new medication started in the 10 weeks prior to participation.
• There are planned changes to their usual treatment during the study period.
• They or their parents are unable to provide informed consent or assent, or to participate in study procedures or assessments in English.
• They do not have a doctor (family physician or specialist) or other primary care provider (e.g. nurse practitioner) providing regular medical care.
• Because there are risks associated with NSAID use in pregnancy, you should avoid becoming pregnant during this study. She should be aware of the risks to an unborn baby/fetus, and will be advised by study staff to work with her study doctor to find the best solution to make sure she does not get pregnant, if she wishes to be in the study.
• They are unable to have blood pressure measured within 2 months prior to enrollment (either on-site at BCCH or by a primary care provider).
• They have an intention of pregnancy.

The UBC Centre for Collaborative Research on Hoarding is doing research to understand perspectives of service providers who at least occasionally assess, intervene, or inspect hoarded homes.

The Provider Perspectives study is recruiting people who encounter hoarding as part of their work in housing, code enforcement, child welfare, older adult services, mental health, or fire prevention. You do not need to be a hoarding specialist or expert (although experts are welcome, too).

The online survey takes about 30 minutes. The questions focus on service providers’ knowledge and perspectives on hoarding and mental illness. Participants will receive a $10 gift card or they can choose to donate the $10 to a charity on our list.Are you Interested? Find out more at https://hoarding.psych.ubc.ca/partners, or email us at hoarding.centre@ubc.ca, and lastly pass this on to your colleagues!

The Oxford Institute of Clinical Psychology Training and Research

University of Oxford, Isis Education Centre, Warneford Hospital, Oxford, OX3 7JX

Researchers: Sam French (Trainee Clinical Psychologist; sam.french@hmc.ox.ac.uk), Professor Paul Salkovskis (Principal Investigator & Director, Oxford Centre for Psychological Health; paul.salkovskis@hmc.ox.ac.uk), Dr Victoria Bream (Consultant Clinical Psychologist, Oxford Cognitive Therapy Centre; victoria.bream@hmc.ox.ac.uk)

Central University Research Ethics Approval (University of Oxford) Reference: R74372/RE001

Can you help us? We are researchers from the Clinical Psychology Department at The University of Oxford, and we are interested in learning more about the link between difficult interpersonal memories and emotional responses.

We are interested in hearing from people who identify as having obsessional and compulsive problems, and those without current experiences of mental health difficulties.

We are hoping to develop a deeper understanding of factors that may contribute to distress in this area, with the hope of tailoring and improving treatments for these individuals.

We are looking for volunteers aged 18 years and over. Participating in the research will take approximately 1 hour, and will involve a short telephone discussion, an experimental task via video, and completion of some questionnaires.

If you are interested and would like more information, please click on the link below. To register your interest or for further information, please contact sam.french@hmc.ox.ac.uk.

The Centre for Collaborative Research on Hoarding wants to know about your experience with a hoarding clean-out. We are looking for individuals with clutter problems and frontline professionals who have experienced or conducted a hoarding clean-out over the past three years. The purpose of our research is to learn from clients and professionals about their experience in order to better improve community hoarding interventions.

What does participation involve?

Share your experience in an online structured interview via Zoom that will take 60 minutes to complete. During the study, we will ask you questions about your experience with a clean-up intervention. If you decide to participate, you will receive a $25 honorarium.

Interested?

Please email hoarding.centre@ubc.ca. A research assistant will contact you to determine if you meet the eligibility criteria. Kate Kysow is in charge of this study, and she is being supervised by the Principal Investigator, Dr. Sheila Woody. Thank you in advance for taking time to complete the study and sharing your valuable perspective with UBC researchers.

Aim: The goal of this research is to investigate racial and ethnic inequalities in obsessive compulsive disorder (OCD) diagnosis and treatment using an online survey. Survey responses will help determine whether or not racial and ethnic minorities with OCD experience symptoms for longer periods of time before receiving treatment than non-Latinx Whites. Responses will also help identify specific barriers to OCD treatment that may differ for different racial/ethnic groups.

Who can take part: We are inviting anyone who meets the following criteria: (1) previous or current OCD diagnosis from a physician or mental health professional based on the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) or the Children’s Yale-Brown Obsessive-Compulsive Scale (CY-BOCS), (2) age of 18 years or older, and (3) status as United States citizen or permanent resident (green card holder).

What we will ask you to do: We will ask participants to complete online questionnaires about sociodemographic information, OCD treatment history, and barriers to OCD treatment. This should take about 10 minutes. You will also have the opportunity to enter your email address if you would like to participate in a follow-up interview to offer deeper insight into barriers to OCD diagnosis and treatment. These interviews will be conducted via telephone to ensure confidentiality.

Compensation: As a thank you for taking part in this study, participants who participate in the follow-up phone interview will be entered in a drawing to win a $100 Amazon gift card.

Contact: If you have any questions, please contact Laura Smestad at lsmestad@antioch.edu.

To take part and find out more, please visit: https://uwartsandsciences.sjc1.qualtrics.com/jfe/form/SV_20hx5W06jSd7tci

The OCD Clinical Research Group is conducting a study on common traits in obsessive compulsive disorder (OCD). It is understood that a high sense of responsibility for one’s self and for others is common for people living with OCD. This study aims to explore whether certain factors in childhood/adolescence may be related to this increased sense of responsibility. Understanding this would give clues to how we can prevent and treat OCD.Who can take part?
English-speaking adults over the age of 18 with access to a computing device. Do I have to have OCD?
No! We are recruiting both people who live with OCD and people who do not have OCD.

What will it involve? 

• A brief telephone interview with a clinical researcher (around 15 minutes).
• The completion of an online questionnaire (around 15 minutes).

What are the advantages to taking part?
Your input with this project will help improve our understanding of OCD so that we can  develop better treatments for others. We unfortunately will not be able to offer  reimbursement for taking part in this study. Who is conducting the research?
This study is being conducted by researchers from the Oxford Institute of Clinical Psychology Training and Research. This study has been reviewed by, and received ethics clearance through, the University of Oxford Central University Research Ethics Committee (Reference number: R74411/RE001). Learn more about the study and take part:
If you are interested in learning more about the study and taking part, please email Dr. Lucas Shelemy at lucas.shelemy@hmc.ox.ac.uk with your name and contact information (email/phone number) and he will get back to you. Thanks!

We are inviting you to take part in a 40-60-minute research study, conducted by the Massachusetts General Hospital and Harvard University, assessing the impact of the coronavirus pandemic on children with PANS/PANDAS and their families. This survey is completely anonymous. It will ask you questions regarding your child’s medical history, you and your child’s experiences in the pandemic, your relationship with your child, and the severity of your child’s PANS/PANDAS symptoms. Please click on the link provided if you are interested in participating. Thank you!

Get paid for participation in research for Children with misophonia (selective sound sensitivity) and Anxiety! Is your child ages 8 to 17? Has your child either received a diagnosis of misophonia or is experiencing impairing anxiety? Baylor College of Medicine is conducting research on the symptomatic presentation and characteristics of children and
adolescents with misophonia or anxiety problems. Incentives will be provided upon completion of each individual online assessments, single in-person session, and two optional follow-up surveys. If you are interested in learning more about this study please contact Gifty Amos Nwankwo at misophonia@bcm.edu or 713-798-1916.

A researcher at Harvard Extension School is seeking participants in a study on Parkinson’s Disease. To participate you must be diagnosed with Parkinson’s. This study requires participation from a caregiver, family member, or partner that is close to the individual with Parkinson’s.

The purpose of this research is to investigate correlations between Obsessive-Compulsive Disorder and Parkinson’s Disease and contribute to potential early diagnostic screening tools for Parkinson’s Disease, as well as potential mental health intervention opportunities.

Participation in this study involves: 

• Completion of an online 10 minute screening survey
• Completion of an online version of the Parkinson’s Disease Questionnaire-39
• A 1.5 hour online semi-structured interview with the researcher, your primary caregiver or parter, and yourself
• Part of this interview is a completion of the Yale-Brown Obsessive Compulsive Survey which is an assessment for OCD symptoms and asks highly sensitive questions in regard to past and present thoughts related to topics of aggression, contamination, sex, hoarding, religion, and symmetry.

Exclusion and Inclusion Criteria: 

Participants are expected to be over the age of 50, individuals with Young Onset Parkinson’s will be excluded due to the small sample size. Additional exclusion criteria: individuals with documented dementia or other neurological degeneration that prevents them from recalling events in the last 10 years will not be included, an inability to understand surveys and interview questions due to lack of literacy or education level would also prevent participation. Individuals with PD and no subsyndromal OCD symptoms will be excluded as well. Only high functioning individuals with the ability to consent will be admitted into the study, Individuals who do not have a caregiver that is able to participate will be excluded as pairs are needed due to the study design.

Take Screening Survey

For more information about this study, please contact the principal investigator, Olesya Luraschi, by phone at 360-521-2531 or email at olesyaluraschi@g.harvard.edu.

Thank you,

Olesya Luraschi

Principal Investigator

Study Title: Obsessive-Compulsive Disorder as an Early Indicator of Parkinson’s Disease: A Multiple Case Study