Although the initial plan of this study by Dr. Whiteside and his team was to understand the treatment effects of cognitive behavioral therapy and medication on OCD through the use… Read more »
A systematic investigation of intensive residential management for severe obsessive compulsive disorder: Predictors of short and long-term outcome
At the time of this study, intensive residential treatment (IRT; a therapy module for severe, treatment-resistant OCD) was recently developed and showed promise for treating serious OCD. Multiple studies by… Read more »
The effects of brief consultation to families of OCD treatment refusers: A pilot outcome study
Although multiple treatment modalities can reduce or remove OCD symptoms, some people with OCD refuse to engage in them. This can be for a variety of reasons, including uncertainty or… Read more »
Multi-site study of CBT treatment failures
Cognitive behavioral therapies (CBT) are a group of evidence-based treatments for OCD, including cognitive therapy, behavioral therapy, exposure and response prevention therapy (ERP). Despite their overall efficacy, some people with… Read more »
Adjunctive glycine for OCD
Although medications for OCD such as serotonin reuptake inhibitors (SRIs) have shown to be effective in reducing symptoms, some patients with OCD experience little reduction. OCD is associated with hyperactivity… Read more »
Measuring the effects of cognitive behavioral treatment on neurochemical compounds in pediatric OCD utilizing proton magnetic resonance spectroscopy
One of the theories behind why OCD occurs was that cortico-striatal dysfunctions in the brain were associated with symptoms. This study by Drs. Whiteside and Port aimed to investigate whether… Read more »
Evaluation of exposure and response prevention with or without parent management training for children with obsessive compulsive disorder and disruptive behavior
Although pediatric OCD presents its own difficult symptoms, prior research showed that almost half of children with OCD also had a comorbid disruptive behavior disorder. This study by Dr. Sukhodolsky… Read more »
Treatment response in OCD to sertraline and aripiprazole as compared to sertraline and placebo
Although selective serotonin reuptake inhibitors (SSRIs) are effective for treating OCD, they do not reduce OCD symptoms for everyone due to a variety of factors. A potential avenue of boosting… Read more »
Improving treatment outcome in obsessive compulsive disorder: Does a motivational enhancement intervention boost efficacy?
Despite the efficacy of exposure and response prevention (ERP) in treating OCD, factors such as treatment refusal, dropping out of treatment, and inability to use treatment gains outside of therapy… Read more »
A double-blind, placebo-controlled trial of N-acetylcysteine in SRI-resistant OCD
Although the initial focus of this study by Dr. Coric and his team was how N-acetylcysteine would supplement the effectiveness of serotonin reuptake inhibitors for treating OCD, this research resulted… Read more »