2008 OCF Grant

Optimization of transcranial magnetic stimulation (TMS) in obsessive compulsive disorder (OCD): A sham controlled randomized clinical trial of MRI-guided TMS

Antonio Mantovani, MD, PhD

Columbia University Medical Center (New York, NY)

Award Amount: $37,642

Methods such as transcranial magnetic stimulation (TMS) aim to decrease symptoms of disorders such as OCD by carefully and non-invasively targeting specific brain regions that are implicated in these disorders.

This study by Dr. Mantovani and his team aimed to assess the efficacy of TMS guided by magnetic resonance imaging (MRI) for treating OCD symptoms. The goal was to improve the use of TMS further by using MRI to guide TMS targeting the supplementary motor area — a brain region that is associated with movement control — in 20 patients with OCD who did not respond to other forms of treatment.