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Celecoxib as an adjunct to treatment as usual in childhood-onset OCD: A double-blind randomized controlled trial

Posted June 13th, 2023 by borislitvin & filed under .

PANDAS/PANS is associated with neuroinflammation that leads to sudden and acute OCD symptoms developing in children, seemingly overnight. Non-steroidal anti-inflammatory drugs (NSAIDs) like celecoxib (brand name “Celebrex”) are increasingly recommended… Read more »

Identifying targets for prevention and early intervention in Obsessive-Compulsive Disorder

Posted June 13th, 2023 by borislitvin & filed under .

Research has found that the risk for developing OCD is not only due to the genes we inherit from our parents, but also from environmental factors. However, it is unclear… Read more »

Correlates of treatment outcome using multimodal neuroimaging in children with PANDAS

Posted June 13th, 2023 by borislitvin & filed under .

Researchers are increasingly interested in the connection between inflammation in the brain and OCD symptoms in both Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal infections (PANDAS) and more typical childhood-onset… Read more »

Optimization of parent-led exposure delivery in pediatric OCD

Posted June 13th, 2023 by borislitvin & filed under .

When children develop OCD, the most effective treatment available for them is cognitive behavioral therapy (CBT) with exposure and response prevention (ERP). Children engage in exposure work where they intentionally… Read more »

Expanding the genetic landscape of pediatric OCD

Posted June 13th, 2023 by borislitvin & filed under .

While the role of genetic factors in the development of OCD has been emphasized through research, more attention is needed to identify specific risk factors and underlying biological pathways. Past… Read more »

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