Initial research suggests that the brain’s endocannabinoid system is involved in the regulation of OCD symptoms and anxiety. Fatty Acid Amide Hydrolase (FAAH) is an enzyme that regulates levels of… Read more »
Deep TMS for obsessive-compulsive disorder: An fMRI study
Deep transcranial magnetic stimulation (dTMS), a non-invasive and generally well-tolerated brain stimulation method, was recently granted FDA clearance for the treatment of OCD after pilot studies, real-world data, and a… Read more »
Personalized neuromodulation for a novel OCD biomarker and treatment
Although multiple treatments for OCD exist, slow symptom decrease, high remission, and significant side effects for some OCD patients limit their efficacy. More research into the precise neural mechanisms and… Read more »
Towards optimal use of internet-delivered interventions for obsessive compulsive disorder
Cognitive behavioral therapy (CBT), including exposure and response prevention (ERP), is a proven and effective treatment for obsessive-compulsive disorder (OCD). However, many people with OCD are unable to access effective… Read more »
Assessing correlates of neuroinflammation in children with PANDAS, obsessive compulsive disorder, and healthy controls using Magnetic Resonance Imaging
Inflammation of the brain is suspected to be present in children with PANDAS, but confirming this hypothesis is difficult. The best tools for revealing brain inflammation expose patients to ionizing… Read more »
Pairing tVNS and exposure and response prevention to improve symptoms of OCD
Cognitive behavioral therapy (CBT) with exposure and response prevention (ERP) is a safe, effective, and proven treatment for OCD. Some researchers believe that ERP’s efficacy lies behind helping patients “un-learn”… Read more »
How disease and medication shape the brain, and how the brain predicts individual treatment response: Learning from global collaboration
Brain imaging has revolutionized our understanding of mental health disorders like OCD by revealing important information about which parts of the brain are impacted by OCD and informing treatment approaches…. Read more »
Dissecting the temporal and causal relationships between OCD and bipolar disorder
Compared to the general population, people with OCD are 10 times more likely to have a bipolar disorder (BPD) diagnosis. Research has shown that BPD comorbidity is associated with more… Read more »