Surgery options such as deep brain stimulation (DBS) surgery can provide relief for patients with severe, treatment-resistant OCD. Cutting edge research has led to the development of new devices that… Read more »
The role of regulatory T cells in Pediatric Acute Onset Neuropsychiatric Syndrome (PANS): With an emphasis on CD39 + subset
Cumulating evidence has shown that PANS is associated with inflammation, dysregulation of immune cells, and importantly for this proposal, autoimmunity. Key inhibitors of autoimmunity are regulatory T cells (Tregs), a… Read more »
A good enough intervention: Testing brief online self-help treatment modules for clinical perfectionism
Clinical perfectionism, a common feature of OCD, leads to problems when individuals set extremely high standards for themselves and harshly criticize themselves for not meeting those standards. This can result… Read more »
Investigating the brain endocannabinoid system in obsessive-compulsive disorder
Initial research suggests that the brain’s endocannabinoid system is involved in the regulation of OCD symptoms and anxiety. Fatty Acid Amide Hydrolase (FAAH) is an enzyme that regulates levels of… Read more »
Deep TMS for obsessive-compulsive disorder: An fMRI study
Deep transcranial magnetic stimulation (dTMS), a non-invasive and generally well-tolerated brain stimulation method, was recently granted FDA clearance for the treatment of OCD after pilot studies, real-world data, and a… Read more »
Personalized neuromodulation for a novel OCD biomarker and treatment
Although multiple treatments for OCD exist, slow symptom decrease, high remission, and significant side effects for some OCD patients limit their efficacy. More research into the precise neural mechanisms and… Read more »
Transcranial magnetic stimulation effects on urge suppression in obsessive-compulsive disorder using individualized targeting of the postcentral gyrus: A proof-of-concept investigation
OCD is usually associated with fear-based obsessions leading to compulsions, however, many individuals with OCD report uncomfortable urge sensations that drive their compulsions (e.g. overwhelming and uncomfortable feeling of contamination… Read more »