Although effective treatments for OCD exist, more than half of people with OCD never receive the care they need, especially if they have financial challenges. Caregivers, who play a critical… Read more »
Nothing to fear: Developing and piloting treatment and training procedures for non-fear-based presentations of obsessive-compulsive disorder
Exposure and response prevention (ERP) mainly focuses on reducing fear, which is a good fit for patients who do compulsions in response to anxiety or to avoid feared outcomes. However,… Read more »
Electrophysiological biomarker characterization in sensing-enabled deep brain stimulation for obsessive-compulsive disorder
Surgery options such as deep brain stimulation (DBS) surgery can provide relief for patients with severe, treatment-resistant OCD. Cutting edge research has led to the development of new devices that… Read more »
Deep TMS for obsessive-compulsive disorder: An fMRI study
Deep transcranial magnetic stimulation (dTMS), a non-invasive and generally well-tolerated brain stimulation method, was recently granted FDA clearance for the treatment of OCD after pilot studies, real-world data, and a… Read more »
Personalized neuromodulation for a novel OCD biomarker and treatment
Although multiple treatments for OCD exist, slow symptom decrease, high remission, and significant side effects for some OCD patients limit their efficacy. More research into the precise neural mechanisms and… Read more »
Transcranial magnetic stimulation effects on urge suppression in obsessive-compulsive disorder using individualized targeting of the postcentral gyrus: A proof-of-concept investigation
OCD is usually associated with fear-based obsessions leading to compulsions, however, many individuals with OCD report uncomfortable urge sensations that drive their compulsions (e.g. overwhelming and uncomfortable feeling of contamination… Read more »
Controlled evaluation of positive family interaction therapy (P-FIT) for children and adolescents with OCD
Dr. Piacentini and his team’s prior research identified poor family cohesion, high conflict, and high blame as significant obstacles to youths with OCD responding to exposure-based CBT. Notably, 92% of… Read more »
D-Cycloserine augmentation of exposure and response prevention treatment for obsessive compulsive disorder
Although cognitive behavior therapy (CBT) has shown to be effective for treating children with OCD, not everyone responds to this treatment. As a result, factors that could help make patients… Read more »
Augmentation of behavioral exposure therapy for obsessive compulsive disorder with D-Cycloserine
While exposure and response prevention (ERP) and cognitive behavioral therapy (CBT) are effective for treating OCD, some patients do not experience a reduction in symptoms. In animal models, d-cycloserine has… Read more »
Comparing the efficacy of 3 forms of CBT for OCD
Cognitive behavioral therapies (CBT) are a category of treatment that have proven to be effective for treating OCD. CBT includes a variety of modalities, including one-on-one and group therapies. This… Read more »