Although cognitive behavioral therapy (CBT) and medication can help alleviate OCD symptoms in most, some individuals with OCD may not benefit fully. Additionally, individuals with OCD frequently report concerns about… Read more »
Cognitive-behavior therapy for comorbid OCD and major depression
Major depressive disorder is a common co-occurring condition with OCD; based on research at the time of the study, 30% of OCD patients also suffered from symptoms of depression. Cognitive… Read more »
Home-based versus office-based behavioral treatment of obsessive compulsive disorder
Given the overall efficacy of exposure and response prevention (ERP) therapy in treating OCD, evaluating whether ERP could be effective at home and familiar settings — where symptoms typically occur… Read more »
The effectiveness of cognitive-behavioral treatment for obsessive compulsive disorder: Do symptom-based subgroups respond differently?
At the time of this study, much research was dedicated to identifying distinct subtypes of OCD. This study by Dr. Calamari and his team intended to test whether there are… Read more »
Cytochrome p450 2D6 polymorphisms/duplications and serotonin uptake inhibitor response in OCD: A pilot study
At the time of this study, serotonin reuptake inhibitors (SRIs) only benefited about 60% of patients who took them for OCD; even then, response was usually partial. This study by… Read more »
The effects of cognitive behavioral treatment on neurochemical compounds in patients with OCD: Evaluation of proton magnetic resonance spectroscopy
Although the initial plan of this study by Dr. Whiteside and his team was to understand the treatment effects of cognitive behavioral therapy and medication on OCD through the use… Read more »
A systematic investigation of intensive residential management for severe obsessive compulsive disorder: Predictors of short and long-term outcome
At the time of this study, intensive residential treatment (IRT; a therapy module for severe, treatment-resistant OCD) was recently developed and showed promise for treating serious OCD. Multiple studies by… Read more »
The effects of brief consultation to families of OCD treatment refusers: A pilot outcome study
Although multiple treatment modalities can reduce or remove OCD symptoms, some people with OCD refuse to engage in them. This can be for a variety of reasons, including uncertainty or… Read more »
Multi-site study of CBT treatment failures
Cognitive behavioral therapies (CBT) are a group of evidence-based treatments for OCD, including cognitive therapy, behavioral therapy, exposure and response prevention therapy (ERP). Despite their overall efficacy, some people with… Read more »
Adjunctive glycine for OCD
Although medications for OCD such as serotonin reuptake inhibitors (SRIs) have shown to be effective in reducing symptoms, some patients with OCD experience little reduction. OCD is associated with hyperactivity… Read more »