At the time of this study, there was a hypothesis that dysfunctions in serotonin (a neurotransmitter responsible for mood, cognition, reward, and memory) were associated with OCD; however, this was… Read more »
Functional MRI activity and inhibition in OCD
OCD has been hypothesized to involve difficulty inhibiting thoughts and behaviors. Prior research has suggested that the brain’s frontal-striatal-thalamic-cortical (FSTC) circuitry plays an important role in regulating behavior, including inhibitory… Read more »
The effects of cognitive behavioral treatment on neurochemical compounds in patients with OCD: Evaluation of proton magnetic resonance spectroscopy
Although the initial plan of this study by Dr. Whiteside and his team was to understand the treatment effects of cognitive behavioral therapy and medication on OCD through the use… Read more »
Clinical and genetics studies of OCD with and without tics
At the time of this study, a key focus of research was exploring the genetics behind OCD and its comorbidities. Genetic association studies were conducted to look at how certain… Read more »
Measuring the effects of cognitive behavioral treatment on neurochemical compounds in pediatric OCD utilizing proton magnetic resonance spectroscopy
One of the theories behind why OCD occurs was that cortico-striatal dysfunctions in the brain were associated with symptoms. This study by Drs. Whiteside and Port aimed to investigate whether… Read more »
Genetic studies of the NMDA regulatory network in OCD including neuroimaging endophenotypes
With growing interest in how glutamate (one of the most important neurotransmitters linked to learning, memory, and mood) and N-methyl-D-aspartate (NMDA; a glutamate receptor in the brain) are connected to… Read more »
Diffusion tensor imaging of OCD
Although neuroimaging techniques such as magnetic resonance imaging existed at the time of this study and could take high-quality pictures of the brain, diffusion tensor imaging (DTI) could visualize the… Read more »
Visual information processing in body dysmorphic disorder
Prior research has suggested that people with body dysmorphic disorder (BDD) differ in their processing of what they see. As BDD is a disorder that is partly defined by high… Read more »
Optimization of transcranial magnetic stimulation (TMS) in obsessive compulsive disorder (OCD): A sham controlled randomized clinical trial of MRI-guided TMS
Methods such as transcranial magnetic stimulation (TMS) aim to decrease symptoms of disorders such as OCD by carefully and non-invasively targeting specific brain regions that are implicated in these disorders…. Read more »
Functional neuroanatomy of body dysmorphic disorder
Neuroimaging research to understand how the brains of people with body dysmorphic disorder (BDD) functioned was limited at the time of this study. This study by Dr. Saxena and his… Read more »