One of the theories behind why OCD occurs was that cortico-striatal dysfunctions in the brain were associated with symptoms. This study by Drs. Whiteside and Port aimed to investigate whether… Read more »
Evaluation of exposure and response prevention with or without parent management training for children with obsessive compulsive disorder and disruptive behavior
Although pediatric OCD presents its own difficult symptoms, prior research showed that almost half of children with OCD also had a comorbid disruptive behavior disorder. This study by Dr. Sukhodolsky… Read more »
Treatment response in OCD to sertraline and aripiprazole as compared to sertraline and placebo
Although selective serotonin reuptake inhibitors (SSRIs) are effective for treating OCD, they do not reduce OCD symptoms for everyone due to a variety of factors. A potential avenue of boosting… Read more »
Improving treatment outcome in obsessive compulsive disorder: Does a motivational enhancement intervention boost efficacy?
Despite the efficacy of exposure and response prevention (ERP) in treating OCD, factors such as treatment refusal, dropping out of treatment, and inability to use treatment gains outside of therapy… Read more »
A double-blind, placebo-controlled trial of N-acetylcysteine in SRI-resistant OCD
Although the initial focus of this study by Dr. Coric and his team was how N-acetylcysteine would supplement the effectiveness of serotonin reuptake inhibitors for treating OCD, this research resulted… Read more »
Double-blind trial of acute and intermediate-term dextro-amphetamine versus caffeine augmentations in treatment-resistant OCD
Despite the variety of medication treatments that exist for OCD, some patients do not respond well to them and experience little to no reduction in their symptoms. This study by… Read more »
Psychosocial treatment of obsessive compulsive disorder in young children
At the time of this study, studies on therapy and medication were not conducted to assess their effectiveness for children with OCD under the age of seven. However, children as… Read more »
A prevention program for postpartum OC symptoms
Postpartum disorders (mental health disorders starting after delivery of a child) require special attention as they can negatively affect not only the mother, but also the child and the family… Read more »
Delivery of Internet treatment for compulsive hoarding (D.I.T.C.H.)
Hoarding disorder (HD) was considered a subtype of OCD at the time of this study. Hoarding symptoms can be treated using cognitive behavioral therapy (CBT). However, at the time of… Read more »
Treatment of compulsive hoarding in older adults
Hoarding disorder (HD) was still considered a subtype of OCD at the time of this grant. Hoarding symptoms pose unique challenges and dangers for older adults. Although cognitive behavioral therapy… Read more »