Despite the efficacy of exposure and response prevention (ERP) in treating OCD, factors such as treatment refusal, dropping out of treatment, and inability to use treatment gains outside of therapy… Read more »
A double-blind, placebo-controlled trial of N-acetylcysteine in SRI-resistant OCD
Although the initial focus of this study by Dr. Coric and his team was how N-acetylcysteine would supplement the effectiveness of serotonin reuptake inhibitors for treating OCD, this research resulted… Read more »
Double-blind trial of acute and intermediate-term dextro-amphetamine versus caffeine augmentations in treatment-resistant OCD
Despite the variety of medication treatments that exist for OCD, some patients do not respond well to them and experience little to no reduction in their symptoms. This study by… Read more »
Psychosocial treatment of obsessive compulsive disorder in young children
At the time of this study, studies on therapy and medication were not conducted to assess their effectiveness for children with OCD under the age of seven. However, children as… Read more »
A prevention program for postpartum OC symptoms
Postpartum disorders (mental health disorders starting after delivery of a child) require special attention as they can negatively affect not only the mother, but also the child and the family… Read more »
Delivery of Internet treatment for compulsive hoarding (D.I.T.C.H.)
Hoarding disorder (HD) was considered a subtype of OCD at the time of this study. Hoarding symptoms can be treated using cognitive behavioral therapy (CBT). However, at the time of… Read more »
Treatment of compulsive hoarding in older adults
Hoarding disorder (HD) was still considered a subtype of OCD at the time of this grant. Hoarding symptoms pose unique challenges and dangers for older adults. Although cognitive behavioral therapy… Read more »
Enhanced cognitive behavioral therapy for OCD: A couple-based approach (2 year study)
Spouses and romantic partners of people with OCD often accommodate their loved ones’ symptoms, which reinforces them despite their belief that they may be helping their loved one. Could including… Read more »
Optimization of transcranial magnetic stimulation (TMS) in obsessive compulsive disorder (OCD): A sham controlled randomized clinical trial of MRI-guided TMS
Methods such as transcranial magnetic stimulation (TMS) aim to decrease symptoms of disorders such as OCD by carefully and non-invasively targeting specific brain regions that are implicated in these disorders…. Read more »
Predicting medication response in obsessive compulsive disorder
A variety of medications exist for OCD, such as selective serotonin reuptake inhibitors (SSRIs) and antidepressants such as clomipramine. However, not all patients respond to these medications equally, with some… Read more »