Even after completing CBT, many patients with hoarding disorder (HD) continue to experience clinically significant hoarding symptoms. While CBT challenges the importance of hoarded objects, it does not address patients’… Read more »
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Use of transcranial direct current stimulation to enhance consolidation of therapeutic learning in obsessive-compulsive disorder (OCD)
While medications and psychotherapy can each help about 60% of OCD patients, troubling symptoms can often persist even among treatment responders. New therapeutic strategies are urgently needed. The top therapeutic… Read more »
Decision-making impairments in OCD: An integrated behavioral economics model
Patients with OCD often view risky situations as aversive, with high rates of avoidance of feared situations and stimuli (e.g., public restrooms, kitchen stoves). However, the research on risk aversion… Read more »
The impact of obsessive-compulsive disorder on education, labor market marginalization, and societal cost
OCD typically emerges in childhood or adolescence, may be chronic, and is associated with marked functional impairment, reduced quality of life, and high economic burden for society. The impact of… Read more »
Obsessive-compulsive symptoms in African American young adults: The roles of racial discrimination and racial identity
Past research has shown that people with OCD experience worsened symptoms when under stress. Some stressors are unique to distinct identities and statuses in a larger society. For African Americans… Read more »
Active avoidance of threat cues and fear extinction in obsessive compulsive disorder
Past research has shown that we can learn to be afraid of things that we encounter, and that we can also modify our fears through exposure. New research has shown… Read more »
A virtual reality study of cognitive biases in body dysmorphic disorder
Previous research has found that people with body dysmorphic disorder (BDD) often assign negative interpretations to neutral or benign social interactions, and may believe that others are judging them or… Read more »
Neural mechanisms of avoidance in exposure and response prevention for OCD
Many patients with OCD who successfully complete ERP treatment experience life-changing improvements in their OCD symptoms. However, as many as 40-50% of patients do not experience a significant recovery. Dr…. Read more »
Identifying the molecular and cellular substrates of OCD using human post-mortem brain
Brain imaging studies in OCD patients have consistently shown abnormal activity in regions involved in decision-making (orbitofrontal cortex [OFC]) and transmission of sensory information (thalamus). The goal of this project… Read more »