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Effect of intranasal oxytocin on social cognition in body dysmorphic disorder
Oxytocin is a hormone that is associated with emotion recognition and social attentional processing. Given the difficulties in emotion regulation and social approach behavior present in people with body dysmorphic… Read more »
Defining the prevalence, impacts, and risk factors of hoarding disorder
In 2012, hoarding disorder (HD) was classified as a disorder separate from OCD in the DSM-5. More information was needed regarding its true prevalence, associated risk factors, and social- and… Read more »
Extinction as a facilitator of cognitive bias modification in pediatric OCD
While therapies such as exposure and response prevention (ERP) can effectively treat OCD in children, not all children see a decrease in symptoms. From a cognitive perspective, OCD is associated… Read more »
2015 Donor-Awarded Research Grants: Acceptance and Commitment Therapy
Prediction, understanding, and treatment of perfectionism using acceptance and commitment therapy Used for OCD and other mental health disorders, acceptance and commitment therapy (ACT) is a form of cognitive behavioral… Read more »
Targeted real-time NIRS-driven neurofeedback: A novel treatment for OCD
Despite a variety of treatments for OCD existing, about a quarter of people with OCD do not experience a substantial decrease in symptoms. However, non-invasive treatments that target certain brain… Read more »
In vivo identification of antibody targets in PANDAS/PANS
At the time of this study, one proposed method by which PANDAS/PANS takes hold in patients is the autoimmune response of antibodies made to fight Group A beta-hemolytic Streptococcus (GABHS;… Read more »
MRS glutamate-stratified treatment of pediatric OCD
Although cognitive behavioral therapy (CBT) is an effective treatment for pediatric OCD, not all patients respond to it equally — with some seeing little to no decrease in symptoms. This… Read more »
Sleep and circadian disturbances as a vulnerability for OCD
Sleep and circadian rhythms (internal regulators of sleep cycles) are crucial for mental health, and disorders such as insomnia have immensely negative consequences on daily functioning and wellbeing. Studies by… Read more »
PANDAS autoantibodies and the blood-brain barrier
Infections with S. pyogenes (GAS) are associated with brain autoimmune disorders: Sydenham’s chorea (SC) and Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections (PANDAS). Autoantibodies form when the immune system fails to… Read more »