Major depressive disorder is a common co-occurring condition with OCD; based on research at the time of the study, 30% of OCD patients also suffered from symptoms of depression. Cognitive… Read more »
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Home-based versus office-based behavioral treatment of obsessive compulsive disorder
Given the overall efficacy of exposure and response prevention (ERP) therapy in treating OCD, evaluating whether ERP could be effective at home and familiar settings — where symptoms typically occur… Read more »
The effectiveness of cognitive-behavioral treatment for obsessive compulsive disorder: Do symptom-based subgroups respond differently?
At the time of this study, much research was dedicated to identifying distinct subtypes of OCD. This study by Dr. Calamari and his team intended to test whether there are… Read more »
Cytochrome p450 2D6 polymorphisms/duplications and serotonin uptake inhibitor response in OCD: A pilot study
At the time of this study, serotonin reuptake inhibitors (SRIs) only benefited about 60% of patients who took them for OCD; even then, response was usually partial. This study by… Read more »
Compulsive hoarding among elderly people
Hoarding disorder (HD) was considered to be a subtype of OCD until the publication of the DSM-5 in 2013. At the time of this study, relatively little was known about… Read more »
The effects of cognitive behavioral treatment on neurochemical compounds in patients with OCD: Evaluation of proton magnetic resonance spectroscopy
Although the initial plan of this study by Dr. Whiteside and his team was to understand the treatment effects of cognitive behavioral therapy and medication on OCD through the use… Read more »
GABHS induced OCD (PANDAS): Analysis of clinical and neurobiological response to antibiotic treatment
Although group A beta-hemolytic streptococcal (GABHS) infections typically cause symptoms such as “strep throat”, research at the time began to look at their connection to PANDAS — the sudden onset… Read more »
A systematic investigation of intensive residential management for severe obsessive compulsive disorder: Predictors of short and long-term outcome
At the time of this study, intensive residential treatment (IRT; a therapy module for severe, treatment-resistant OCD) was recently developed and showed promise for treating serious OCD. Multiple studies by… Read more »
The effects of brief consultation to families of OCD treatment refusers: A pilot outcome study
Although multiple treatment modalities can reduce or remove OCD symptoms, some people with OCD refuse to engage in them. This can be for a variety of reasons, including uncertainty or… Read more »
Clinical and genetics studies of OCD with and without tics
At the time of this study, a key focus of research was exploring the genetics behind OCD and its comorbidities. Genetic association studies were conducted to look at how certain… Read more »